diff --git a/gnu/packages/guile-xyz.scm b/gnu/packages/guile-xyz.scm
index c4d6d38b9b..b161d335ba 100644
--- a/gnu/packages/guile-xyz.scm
+++ b/gnu/packages/guile-xyz.scm
@@ -1190,9 +1190,7 @@ messaging library.")
                         ;; command.
                         (substitute* "src/hmac.scm"
                           (("openssl")
-                           (string-append (assoc-ref inputs "openssl")
-                                          "/bin/openssl")))
-                        #t))
+                           (search-input-file inputs "/bin/openssl")))))
 
                     ;; XXX: The code uses 'include' to include its own source
                     ;; files, and "-L src" isn't enough in this case.
@@ -1314,7 +1312,9 @@ tracker's SOAP service, such as @url{https://bugs.gnu.org}.")
              version ".tar.lz"))
        (sha256
         (base32
-         "1rc8r0fgvflnyq5ckl7ii8sghpsgpkzxa8vskjr1ak2kyar6m35k"))))
+         "1rc8r0fgvflnyq5ckl7ii8sghpsgpkzxa8vskjr1ak2kyar6m35k"))
+       (patches
+        (search-patches "guile-email-fix-tests.patch"))))
     (build-system gnu-build-system)
     (native-inputs
      `(("pkg-config" ,pkg-config)
@@ -2989,7 +2989,7 @@ chunks can be expressions as well as simple tokens.")
                (("/usr/local/lib/guile")
                 (string-append (assoc-ref outputs "out") "/lib/guile"))
                (("/usr/local/include/guile")
-                (string-append (assoc-ref inputs "guile") "/include/guile"))
+                (search-input-directory inputs "/include/guile"))
                (("-L/usr/local/lib")
                 (string-append "-L" (assoc-ref inputs "guile") "/lib")))
              #t))
@@ -3388,7 +3388,7 @@ API.")
        ("perl" ,perl)
        ("pkg-config" ,pkg-config)
        ("texinfo" ,texinfo)
-       ("texlive" ,(texlive-union (list texlive-generic-epsf)))))
+       ("texlive" ,(texlive-updmap.cfg (list texlive-epsf)))))
     (inputs
      `(("dbus-glib" ,dbus-glib)
        ("guile" ,guile-3.0)
@@ -3672,7 +3672,7 @@ feature-set, fully programmable in Guile Scheme.")
        ("vigra-c" ,vigra-c)
        ("guile" ,guile-2.2)))
     (native-inputs
-     `(("texlive" ,(texlive-union (list texlive-booktabs
+     `(("texlive" ,(texlive-updmap.cfg (list texlive-booktabs
                                         texlive-lm
                                         texlive-siunitx
                                         texlive-standalone
@@ -4066,7 +4066,14 @@ over, or update a value in arbitrary data structures.")
        (file-name (git-file-name name version))
        (sha256
         (base32
-         "16k61f1jn3g48jaf3730b9l0izr5j933jzyri73nmcnjd09gm35i"))))
+         "16k61f1jn3g48jaf3730b9l0izr5j933jzyri73nmcnjd09gm35i"))
+       (modules '((guix build utils)))
+       (snippet
+        ;; Guile >= 3.0.7 no longer uses libltdl so we need to explicitly add
+        ;; ".libs" so that 'load-extension' finds the '.so' file.
+        '(substitute* "pre-inst-env.in"
+           (("^LD_LIBRARY_PATH=.*$")
+            "LD_LIBRARY_PATH=\"$abs_top_builddir/.libs\"\n")))))
     (build-system gnu-build-system)
     (arguments
      '(#:make-flags '("GUILE_AUTO_COMPILE=0"))) ; to prevent guild warnings
@@ -4737,8 +4744,8 @@ schedulers.")
                            "yaml/libyaml.scm"
                            ;; This file is mismatched with the generated FFI code.
                            "yaml/ffi-help-rt.scm"))
-               (copy-file (string-append (assoc-ref inputs "nyacc")
-                                         "/share/guile/site/3.0/system/ffi-help-rt.scm")
+               (copy-file (search-input-file
+                           inputs "/share/guile/site/3.0/system/ffi-help-rt.scm")
                           "yaml/ffi-help-rt.scm")
                (substitute* "yaml/ffi-help-rt.scm"
                  (("system ffi-help-rt") "yaml ffi-help-rt"))